Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Leaky Scanning02:28

Leaky Scanning

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...
Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
Two-Dimensional Microscopy in Microbiology01:29

Two-Dimensional Microscopy in Microbiology

Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nanoengineering conductive soft interfaces for electrogenic cell interactions: a review of materials, fabrication and functionalisation strategies.

Biofabrication·2026
Same author

Integration of 3D-Printed Micro/Nanostructures with Interdigitated Electrodes for Low-Matrix-Effect Sensing.

ACS applied materials & interfaces·2025
Same author

Electroactive nanoinjection platform for intracellular delivery and gene silencing.

Journal of nanobiotechnology·2023
Same author

Engineering Efficient CAR-T Cells via Electroactive Nanoinjection.

Advanced materials (Deerfield Beach, Fla.)·2023
Same author

Ultra-high-resolution greyscale fluorescence images <i>via</i> UV-exposure of thin flexible phosphor films.

Nanoscale·2023
Same author

Intracellular immunoglobulin A (icIgA) in protective immunity and vaccines.

Scandinavian journal of immunology·2023
Same journal

Tuning Piezoelectricity and Pyroelectricity in Poly(vinylidene fluoride) through Ionic Liquid Anion-Size Directed Polymorph and Interface Engineering.

ACS applied materials & interfaces·2026
Same journal

Adsorption-Induced Ferroelectric Symmetry Breaking in Two-Dimensional CuInP<sub>2</sub>S<sub>6</sub>.

ACS applied materials & interfaces·2026
Same journal

Nanocomplexes Integrated into a Polymeric Bilayer Film Enhance Buccal Permeation of a GLP-1 Peptide Analogue.

ACS applied materials & interfaces·2026
Same journal

Correction to "Multienzyme Active Nanozyme for Efficient Sepsis Therapy through Modulating Immune and Inflammation Inhibition".

ACS applied materials & interfaces·2026
Same journal

A Programmable Perfusion Platform with Temperature Monitoring Achieves Multiscale Cryopreservation.

ACS applied materials & interfaces·2026
Same journal

Oral Delivery of Mesenchymal Stem Cell-Derived Extracellular Vesicles To Treat Intestinal Inflammation.

ACS applied materials & interfaces·2026
See all related articles

Related Experiment Video

Updated: Jun 23, 2026

Using a Pan-Viral Microarray Assay Virochip to Screen Clinical Samples for Viral Pathogens
13:45

Using a Pan-Viral Microarray Assay Virochip to Screen Clinical Samples for Viral Pathogens

Published on: April 27, 2011

18.9K

Microsphere-Enabled Micropillar Array for Whispering Gallery Mode Virus Detection.

Bin Guan1,2, Tuck-Weng Kok3, Nicolas Riesen1,2

  • 1Future Industries Institute, STEM, University of South Australia, Mawson Lakes, SA 5095, Australia.

ACS Applied Materials & Interfaces
|February 21, 2024
PubMed
Summary
This summary is machine-generated.

This study introduces a rapid, open microfluidic platform for detecting influenza A viruses using whispering gallery mode resonators. This point-of-care technology enables quick diagnosis and public health monitoring.

Keywords:
evaporationmicropillar arrayoptofluidic sensorspatterningvirus detectionwhispering gallery modes

More Related Videos

Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

9.4K
Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays
09:58

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays

Published on: June 23, 2022

2.1K

Related Experiment Videos

Last Updated: Jun 23, 2026

Using a Pan-Viral Microarray Assay Virochip to Screen Clinical Samples for Viral Pathogens
13:45

Using a Pan-Viral Microarray Assay Virochip to Screen Clinical Samples for Viral Pathogens

Published on: April 27, 2011

18.9K
Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

9.4K
Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays
09:58

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays

Published on: June 23, 2022

2.1K

Area of Science:

  • Optofluidics
  • Biosensing
  • Nanotechnology

Background:

  • Rapid pathogen detection is crucial for timely patient management and public health.
  • Existing methods for influenza virus detection can be time-consuming and require complex laboratory setups.

Purpose of the Study:

  • To develop and demonstrate an open microfluidic platform for the rapid, sensitive detection of influenza viruses.
  • To integrate whispering gallery mode (WGM) microsphere resonators with microfluidics for enhanced biosensing.

Main Methods:

  • An open microfluidic chip with micropillar arrays was designed to trap WGM microsphere resonators precoated with influenza A antibodies.
  • Evaporation-driven flow was utilized to transport microliter volumes of sample to the resonators.
  • Surface wettability of the micropillar array was chemically modified to optimize sample flow and enhance detection sensitivity.

Main Results:

  • The platform achieved specific detection of influenza A viruses within 15 minutes.
  • The sensor demonstrated a linear response to varying concentrations of influenza A viruses.
  • The system required only a few microliters of sample for analysis.

Conclusions:

  • The developed optofluidic sensing platform offers a promising solution for rapid point-of-care influenza virus detection.
  • The integration of microfluidics and WGM resonators enhances sensitivity and speed for pathogen analysis.
  • This technology has the potential to significantly improve patient management and public health surveillance for influenza outbreaks.