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Updated: Jul 2, 2025

Trajectory Data Analyses for Pedestrian Space-time Activity Study
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Recent Advances in Group-Based Trajectory Modeling for Clinical Research.

Daniel S Nagin1, Bobby L Jones2, Jonathan Elmer3

  • 1Heinz College, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA;

Annual Review of Clinical Psychology
|February 21, 2024
PubMed
Summary
This summary is machine-generated.

Group-based trajectory modeling (GBTM) helps identify patient groups with similar health journeys. Recent advances enhance its use in clinical research for better outcome prediction and patient classification.

Keywords:
finite mixture modelingjoint trajectory modelingmultitrajectory modelingprediction

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Area of Science:

  • Clinical Psychology
  • Biostatistics
  • Longitudinal Data Analysis

Background:

  • Group-based trajectory modeling (GBTM) is a powerful tool for analyzing longitudinal data.
  • Its categorical nature is well-suited for clinical psychology and medicine, aiding in patient classification.
  • However, several advanced capabilities remain underutilized in clinical research.

Purpose of the Study:

  • To review recent advancements in GBTM.
  • To highlight underappreciated capabilities of GBTM for clinical research.
  • To provide guidance on selecting the optimal number of trajectory groups.

Main Methods:

  • Review of recent literature on group-based trajectory modeling.
  • Discussion of advanced GBTM features including handling attrition, joint and multi-trajectory models, beta distribution, and outcome prediction.
  • Exploration of methods for determining the number of trajectory groups.

Main Results:

  • GBTM offers advanced features like handling nonrandom attrition and joint/multitrajectory modeling.
  • The beta distribution enhances modeling flexibility.
  • GBTM can associate trajectories with future outcomes and estimate outcome probabilities.
  • Methods for selecting the number of trajectory groups are discussed.

Conclusions:

  • Recent advances significantly expand the utility of GBTM in clinical research.
  • Underappreciated GBTM capabilities can improve patient classification and outcome prediction.
  • Further adoption of these advanced methods will enhance clinical psychology and medicine.