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Predictive And Prognostic Markers
Comparative Analysis Of Electrochemical And Optical Sensors For Detection Of Chronic Wounds Biomarkers: A Review.

Home
Research Domains
Biomedical And Clinical Sciences
Oncology And Carcinogenesis
Predictive And Prognostic Markers
Comparative Analysis Of Electrochemical And Optical Sensors For Detection Of Chronic Wounds Biomarkers: A Review.

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Comparative analysis of electrochemical and optical sensors for detection of chronic wounds biomarkers: A review.

Fátima A R Mota¹, Marieta L C Passos¹, João L M Santos¹

¹LAQV, REQUIMTE, Department of Chemical Sciences, Laboratory of Applied Chemistry, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, no 228, Porto, 4050-313, Portugal.

Biosensors & Bioelectronics

|February 21, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Chronic wounds require objective monitoring. This review explores chronic wound biomarkers and compares electrochemical and optical sensors for their detection, aiming to improve patient care.

Keywords:

Bioensors Biomarkers Chronic wounds Electrochemical

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Area of Science:

Biomaterials Science
Medical Diagnostics
Wound Healing Research

Background:

Chronic wounds (CW) pose significant healthcare challenges due to delayed healing and complications.
Current assessment methods for CW are often subjective and lack inter-observer reliability.
Objective monitoring of CW healing is crucial for effective treatment and preventing deterioration.

Purpose of the Study:

To review the role of biomarkers in objectively assessing chronic wound status and predicting healing outcomes.
To compare electrochemical and optical sensors for the detection of chronic wound biomarkers.
To highlight the potential of these technologies for advancing wound care.

Main Methods:

Literature review of chronic wound biomarkers and their significance.

Comparative analysis of electrochemical and optical sensing technologies for biomarker detection.

Discussion of sensor characteristics including sensitivity, specificity, portability, and cost-effectiveness.

Main Results:

Biomarkers offer quantitative measures for wound healing, inflammation, infection, and regeneration.
Both electrochemical and optical sensors show potential for detecting CW biomarkers.
Key differences in detection capabilities and suitability for point-of-care applications were identified.

Conclusions:

Biomarker identification is advancing personalized chronic wound management.
Electrochemical and optical sensors offer promising avenues for accurate and sensitive biomarker detection.
Further research and development in sensor technology can significantly improve patient outcomes in chronic wound care.