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Updated: Jul 2, 2025

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

Published on: August 5, 2022

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Identification of a conserved α-helical domain at the N terminus of human DNA methyltransferase 1

Qi Hu1, Maria Victoria Botuyan1, Georges Mer2

  • 1Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.

The Journal of Biological Chemistry
|February 21, 2024
PubMed

Keywords:
DNA methylationDNMT1NMR spectroscopyepigeneticsnew protein domain foldsmall-angle X-ray scattering

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