Study of human red cell NADH diaphorase (Dia1) in the Italian population

A total of about 4,500 individuals from Northern, Central and Southern Italy have been analyzed for red cell NADH diaphorase. The results show that the Italians differ significantly (p less than 0.005) from the other examined populations of European origin by showing a higher frequency of the Dia2 allele (6.4%) and a lower frequency of other Dia variants (0.6%).