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Radiotherapy for successful symptom control in recurrent refractory endometriosis: A case report
Febin Antony1, Jomon Raphael Chalissery1, Sareena Gilvaz2
1Department of Radiation Oncology, Amala Institute of Medical Sciences, Thrissur, Kerala, India.
Journal of Cancer Research and Therapeutics
|February 22, 2024
Summary
Radiotherapy effectively treated a patient with recurrent, refractory endometriosis unresponsive to standard therapies. This approach led to symptom regression and sustained relief for six months, improving quality of life.
Area of Science:
- Gynecology
- Oncology
- Radiotherapy
Background:
- Endometriosis is a chronic inflammatory gynecological condition with frequent symptom recurrence despite medical or surgical treatments.
- Refractory endometriosis poses a significant challenge, often requiring novel therapeutic strategies.
Observation:
- A case of recurrent, refractory endometriosis was treated with pelvic radiotherapy.
- The patient had not responded to conventional therapies.
Findings:
- Low-dose radiotherapy (30Gy in 10 fractions using 6MV photons) was administered, encompassing the pelvic region and ovarian remnant.
- Symptoms resolved within one week of treatment.
Implications:
- Radiotherapy may offer a viable treatment option for refractory endometriosis.
- Further research is warranted to explore radiotherapy's role in managing endometriosis, potentially through its anti-inflammatory and ovarian ablation effects.
