Geriatric nutritional risk index as a predictor for postoperative complications in patients with solid cancers: a meta-analysis
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View abstract on PubMed
Summary
This summary is machine-generated.The Geriatric Nutritional Risk Index (GNRI) effectively predicts postoperative complications in solid cancer patients. Low GNRI scores indicate a significantly higher risk of adverse outcomes, including infections and respiratory issues.
Area Of Science
- Oncology
- Geriatric Medicine
- Surgical Outcomes
Background
- The Geriatric Nutritional Risk Index (GNRI) is widely used for solid cancer prognosis.
- Its predictive value for postoperative complications in these patients remains under investigation.
Approach
- A systematic literature search was conducted across electronic databases up to May 2023.
- A meta-analysis of 11 studies involving 11,002 patients was performed.
- Odds ratios (OR) with 95% confidence intervals (CI) were used to assess GNRI's impact.
Key Points
- Low GNRI is associated with a significantly higher risk of overall postoperative complications (OR=2.51).
- Patients with low GNRI face increased risks of severe complications (Clavien-Dindo grade ≥2, OR=2.24), infections (OR=1.85), and respiratory complications (OR=2.94).
Conclusions
- The GNRI serves as a valuable predictor for postoperative complications in patients with solid cancer.
- This meta-analysis confirms the GNRI's utility in identifying high-risk patients.
- Early nutritional assessment using GNRI can aid in proactive management strategies.
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