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Related Concept Videos

Accessory Structures of the Skin: Sebaceous Glands01:21

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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
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The testes, also known as testicles, are the male gonads. They are housed within the scrotum, a sac-like structure located beneath the penis. The scrotum's primary role is to regulate the temperature of the testes, which is crucial for sperm production.
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
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Accessory Structures of the Skin: Hair and Hair Follicles01:16

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Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
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Related Experiment Video

Updated: Jul 2, 2025

Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep
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Scrotal nodular scabies.

Bo Sang1, Zehu Liu1, Xiujiao Xia1

  • 1Department of Dermatology, Hangzhou Third People's Hospital Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University Hangzhou China.

Clinical Case Reports
|February 22, 2024
PubMed
Summary
This summary is machine-generated.

Scabies is a contagious skin disease caused by mites. Microscopic diagnosis can be challenging, especially for nodular scabies, requiring skilled operators to detect burrows accurately.

Keywords:
mite eggnodulescabies

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Area of Science:

  • Dermatology
  • Parasitology
  • Infectious Diseases

Background:

  • Scabies is a highly contagious parasitic skin infestation.
  • Common lesions include papules (2-3 mm solid lesions).
  • Nodular scabies represents a less common but challenging clinical presentation.

Observation:

  • Microscopy is frequently negative in clinically diagnosed nodular scabies.
  • Diagnostic accuracy relies heavily on operator expertise.
  • Identifying burrows and extracting appropriate material are critical for microscopy.

Findings:

  • The sensitivity of microscopic diagnosis for scabies, particularly nodular forms, is operator-dependent.
  • Negative microscopy does not exclude scabies, especially in complex cases.
  • Challenges exist in the reliable detection of scabies mites and their products via standard microscopy.

Implications:

  • Clinical diagnosis remains crucial for nodular scabies.
  • Improved training for microscopy operators may enhance diagnostic accuracy.
  • Further research into more sensitive diagnostic methods for scabies is warranted.