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Acute Kidney Injury Among COVID-19-Positive Patients Is Associated With Higher Mortality: A Single-Center Experience
Torki Al Otaibi1, Ayman Nagib, Prasad Nair
1From Hamed Alessa Organ Transplant Center, Kuwait, Kuwait.
Summary
Acute kidney injury (AKI) is common in hospitalized COVID-19 patients, particularly those with hypertension and diabetes. AKI significantly increases the risk of mechanical ventilation and mortality, especially in older individuals.
Area of Science:
- Nephrology
- Infectious Diseases
- Critical Care Medicine
Background:
- Renal complications of COVID-19 require further investigation.
- Acute kidney injury (AKI) is a significant concern in hospitalized COVID-19 patients.
Purpose of the Study:
- To determine the prevalence of AKI in hospitalized COVID-19 patients.
- To analyze the impact of AKI on patient outcomes.
Main Methods:
- Retrospective evaluation of 586 hospitalized COVID-19 patients.
- Classification of AKI based on Kidney Disease Improving Global Outcomes (KDIGO) guidelines.
- Comparison of outcomes between patients with and without AKI.
Main Results:
- 45.5% of COVID-19 patients developed AKI.
- AKI patients had higher rates of diabetes, hypertension, and ischemic heart disease.
- AKI was associated with increased sepsis, shock, acute respiratory distress syndrome, mechanical ventilation, and overall mortality (63.2% vs 31.1%).
Conclusions:
- AKI prevalence in COVID-19 is higher than previously reported.
- Risk factors for AKI include hypertension, diabetes, male sex, and older age.
- AKI significantly worsens outcomes in COVID-19 patients, with high mortality in severe cases.
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