Budd-Chiari syndrome presenting as sudden infant death

Budd-Chiari syndrome rarely occurs in infants. We report a case of a 1-month-old female infant who presented as a sudden infant death and was found at autopsy to have thrombi occluding both hepatic veins. Microscopically the liver showed perivenular fibrosis extending into the lobule and central venous congestion consistent with Budd-Chiari syndrome.