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Taxonomy development for term standardization in activity resulting from medication review processes: a Delphi study

Mohammed S Alharthi1, Sion Scott2, Carmel Hughes3

  • 1Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif 21947, Saudi Arabia.

The International Journal of Pharmacy Practice
|February 22, 2024
PubMed
Abstract

Insights

Standardized terms for medication review activities were developed to improve research consistency. This international taxonomy will help compare medication review services and their impact effectively.

Area of Science:

  • Pharmacology
  • Health Services Research
  • Clinical Pharmacy

Background:

  • Medication review (MR) is a critical process for assessing drug safety and effectiveness.
  • Inconsistent terminology in MR research hinders comparisons between studies and understanding of service impact.

Purpose of the Study:

  • To establish an international taxonomy of standardized terms and activity definitions for medication reviews.

Main Methods:

  • A three-stage Delphi consensus study involving international medication review experts.
  • Systematic review to identify MR activity terms, followed by expert rating and feedback on a Likert scale.
  • Consensus defined as 75% panel agreement, with iterative refinement of definitions based on feedback.

Main Results:

  • Seven experts from four countries participated.
  • Consensus was reached on terms including 'Medication' as a descriptor.
  • Key MR activity terms agreed upon: discontinue medication, start medication, dose increase, dose decrease, dosage form change, medication safety and efficacy monitor, and Educate.

Conclusions:

  • A standardized set of medication review activity terms and definitions has been selected for global adoption.
  • This standardization will enable meaningful comparisons of process evaluations across diverse settings in future MR research.
Keywords:
consensusmedication reviewprocess evaluationstandardizationtaxonomy

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