Related Experiment Video
Updated: Jul 2, 2025
09:42
Using Continuous Data Tracking Technology to Study Exercise Adherence in Pulmonary Rehabilitation
Published on: November 8, 2013
13.6K
Prediction model protocols indicate better adherence to recommended guidelines for study conduct and reporting.
Paula Dhiman1, Jie Ma1, Shona Kirtley1
1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Centre for Statistics in Medicine, University of Oxford, Oxford, OX3 7LD, UK.
Journal of Clinical Epidemiology
|February 22, 2024
Summary
Protocols for prediction model studies are rare and seldom public. Available protocols are generally well-reported, suggesting improved study methods and reporting quality in prediction modeling research.
Area of Science:
- Medical Research Methodology
- Health Informatics
- Biostatistics
Background:
- Protocols are crucial for research, particularly for prediction models, but their completeness is vital.
- Omissions in published protocols can hinder the reliability of prediction model studies.
Purpose of the Study:
- To assess the reporting quality and content of published prediction model study protocols.
- To evaluate the adherence to methodological recommendations in these protocols.
Main Methods:
- A systematic search of MEDLINE, Embase, and Web of Science was conducted for prediction model study protocols.
- Protocols published between January 1, 2022, and June 30, 2022, were screened.
- Data extraction was guided by the Transparent Reporting of a multivariable prediction model of Individual Prognosis Or Diagnosis (TRIPOD) statement.
Main Results:
- Thirty protocols were identified, primarily for model development (28) with some for validation (6).
- Most protocols were open access, with 15 reporting prospective data collection and 21 planning for clustered data.
- Key details like sample size, study registration, ethics approval, and data sharing plans were variably reported.
Conclusions:
- Publicly available protocols for prediction model studies are infrequent.
- The reviewed protocols demonstrated good reporting standards, aligning with current recommendations.
- Well-reported protocols likely contribute to enhanced quality in the subsequent prediction model studies.
Related Concept Videos
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
126
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
126
01:26Types of Reports III: Telephone and Verbal Reports
741
Telephone and Verbal Reports in healthcare settings are two communication methods for conveying therapeutic instructions from healthcare providers to nurses or other healthcare staff.
Here's an overview of each type:
Telephone Orders
Here's an overview of each type:
Telephone Orders
741
01:56Ethics in Research
23.0K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
23.0K
01:15Assumptions of Survival Analysis
127
Survival models analyze the time until one or more events occur, such as death in biological organisms or failure in mechanical systems. These models are widely used across fields like medicine, biology, engineering, and public health to study time-to-event phenomena. To ensure accurate results, survival analysis relies on key assumptions and careful study design.
127
01:11Guidelines for Writing Outcome
2.8K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
2.8K
01:20Study Designs in Epidemiology
217
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
217