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Related Experiment Videos

[The menopause and bone metabolism].

P D Delmas

    Revue Francaise De Gynecologie Et D'Obstetrique
    |March 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Distinguishing between osteopenia and osteoporosis is crucial for bone health. Early identification of individuals at risk for osteoporosis can guide preventative strategies, especially in postmenopausal women.

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    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
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    Effectiveness of risedronate and alendronate on nonvertebral fractures: an observational study through 2 years of therapy.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2013
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    The use of different dual X-ray absorptiometry brands in a multicenter clinical trial: consequences and limits.

    Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry·2013
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    Effect of oral monthly ibandronate on bone microarchitecture in women with osteopenia-a randomized placebo-controlled trial.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2012
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    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2011
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    Association of bone microarchitecture with parathyroid hormone concentration and calcium intake in men: the STRAMBO study.

    European journal of endocrinology·2011

    Area of Science:

    • Bone physiology and aging.
    • Endocrinology and hormone replacement therapy.
    • Geriatric medicine and skeletal health.

    Context:

    • Osteopenia is a common physiological process affecting both sexes after age 40.
    • Osteoporosis, characterized by vertebral compression fractures, develops when osteopenia reaches a critical threshold.
    • Bone loss accelerates in women during and after menopause, influenced by estrogen levels.

    Purpose:

    • To differentiate between osteopenia and osteoporosis.
    • To highlight the accelerated bone loss in women post-menopause.
    • To underscore the need for a practical method to identify individuals at risk for osteoporosis.

    Summary:

    • Osteopenia is a physiological decline in bone density, while osteoporosis involves fractures due to severe bone loss.

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  • Estrogen therapy can mitigate bone loss in women for several years, and calcium supplements slow decline by 50%.
  • The limitations of current treatments necessitate a reliable method for distinguishing at-risk individuals from those not threatened by osteoporosis.

    • Impact:

    • Facilitates earlier and more accurate diagnosis of osteoporosis.
    • Informs personalized treatment strategies for bone density management.
    • Aids in identifying individuals who would benefit most from preventative interventions.