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Updated: Jul 2, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Marsupialization as an alternative to reconstruction in endoscopic skull base surgery. How I do it
Luca Ferlendis1, Bianca Bossi2, Paolo Castelnuovo3
1Division of Neurosurgery, Department of Biotechnology and Life Sciences, University of Insubria, Ospedale Di Circolo E Fondazione Macchi, 21100, Varese, Italy. luca.ferlendis@gmail.com.
Background:
To treat extradural solid-cystic lesions of the ventral skull base, a pedicled nasoseptal flap (NSF) maintains patency of the marsupialized cavity and prevents restenosis and cyst recurrence.
Methods:
The authors provide a step-by-step description of the surgical technique valid in different lesions of the skull base, all treated via the endoscopic endonasal approach (EEA). The application is demonstrated by an operative video.
Conclusion:
In selected lesions, endoscopic marsupialization using an NSF ensures drainage and ventilation of the surgical cavity. Re-epithelialization provided by a pedicled flap is a viable alternative to multilayer skull base reconstruction.

