Related Experiment Video
Updated: Jul 2, 2025
Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications
Published on: December 8, 2015
Electron Beam Powder Bed Fusion of Ti-48Al-2Cr-2Nb Open Porous Scaffold for Biomedical Applications: Process
Manuela Galati1, Maria Laura Gatto2, Nora Bloise3,4
1Department of Management and Production Engineering (DIGEP), Integrated Additive Manufacturing Center (IAM)-Politecnico di Torino, Torino, Italy.
Abstract:
Titanium aluminide (TiAl)-based intermetallics, especially Ti-48Al-2Cr-2Nb, are a well-established class of materials for producing bulky components using the electron beam powder bed fusion (EB-PBF) process. The biological properties of Ti-48Al-2Cr-2Nb alloy have been rarely investigated, specifically using complex cellular structures. This work investigates the viability and proliferation of NIH-3T3 fibroblasts on Ti-48Al-2Cr-2Nb dodecahedral open scaffolds manufactured by the EB-PBF process. A process parameter optimization is carried out to produce a fully dense part. Then scaffolds are produced and characterized using different techniques, including scanning electron microscopy and X-ray tomography. In vitro viability tests are performed with NIH-3T3 cells after incubation for 1, 4, and 7 days. The results show that Ti-48Al-2Cr-2Nb represents a promising new entry in the biomaterial field.
