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Correction: A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven

Shubhendu Palei1, Jörn Weisner1, Melina Vogt1

  • 1Department of Chemistry and Chemical Biology, TU Dortmund University and, Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW) Otto-Hahn Str. 4a 44227 Dortmund Germany guido.clever@tu-dortmund.de daniel.rauh@tu-dortmund.de daniel.summerer@tu-dortmund.de.

RSC Medicinal Chemistry
|February 23, 2024
PubMed

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Enzyme Inhibition01:30

Enzyme Inhibition

Inhibitors are molecules that reduce enzyme activity by binding to the enzyme. In a normally functioning cell, enzymes are regulated by a variety of inhibitors. Drugs and other toxins can also inhibit enzymes. Some inhibitors bind to the enzyme’s active site, while others inhibit enzymatic activity by binding to other sites on the protein structure.