Related Experiment Video
Updated: May 6, 2026

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
Published on: April 2, 2012
[Herpes simplex factors: Literature review]
Lisette Begazo1, Alysson Morante1, Carlos Espinoza Montes1
1Carrera de Estomatología, Facultad de Ciencias de la Vida y Salud. Universidad Científica del Sur, Lima, Perú. 100062307@cientifica.edu.pe, 100063806@ucientifica.edu.pe, cespinozam@cientifica.edu.pe Universidad Científica del Sur Carrera de Estomatología Facultad de Ciencias de la Vida y Salud Universidad Científica del Sur Lima Peru 100062307@cientifica.edu.pe 100063806@ucientifica.edu.pe cespinozam@cientifica.edu.pe.
Abstract:
Herpes simplex virus, after the first infection, can remain dormant in the lymph nodes and reactivate at any time due to certain factors and/or stimuli causing effects in the patient. The purpose of this literature review is to update scientific information on the factors that predispose to the reactivation of herpes simplex virus. A comprehensive literature review was conducted in the LILACS, SciELO, PubMed, Scopus and the following keywords were used: herpes simplex, reactivation, latency and risks. A factor is reactivation by immunosuppression due to the intake of immunosuppressants or oncological therapy. Another factor is psychological stress, in which the hormones released act on mediating signs of reactivation. Sun exposure that reactivates the virus in infected neurons and infection in pregnant women can trigger complications in the fetus and delivery.
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Factors Affecting Drug Response: Overview
Sexually Transmitted Infections
Infectious Diseases and Their Occurrence
Cytomegalovirus Disease
Encephalitis ll: Pathophysiology

