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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
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Presence of Residual Cardiac Thrombus Predicts Poor Outcome in Cardioembolic Stroke After Reperfusion Therapy
Tingxia Zhang1, Huan Zhou1, Jiansheng Yang1
1Department of Neurology The 2nd Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China.
Journal of the American Heart Association
|February 23, 2024
Summary
Residual cardiac thrombus is found in about one-third of stroke patients post-reperfusion therapy. This finding is linked to worse clinical outcomes, highlighting its importance in cardioembolic stroke management.
Area of Science:
- Cardiology
- Neurology
- Radiology
Background:
- Acute cardiogenic cerebral embolism can leave residual cardiac thrombus post-reperfusion.
- Investigating residual thrombus and its clinical impact is crucial.
Purpose of the Study:
- To determine the occurrence of residual cardiac thrombus in cardioembolic stroke patients after reperfusion.
- To analyze the association between residual cardiac thrombus and clinical outcomes.
Main Methods:
- Prospective data collection of cardioembolic stroke patients.
- Two-phase cardiac computed tomography (CT) within 7 days of reperfusion.
- Defined residual cardiac thrombus as a filling defect on both early- and late-phase CT images.
Main Results:
- 94 out of 303 patients (31.0%) had residual cardiac thrombus.
- Residual cardiac thrombus was associated with poor clinical outcome (OR, 1.951; P=0.041).
- Circulatory stasis and composite endpoint events were not correlated with residual cardiac thrombus.
Conclusions:
- Residual cardiac thrombus is present in approximately one-third of patients post-reperfusion therapy for cardioembolic stroke.
- The presence of residual cardiac thrombus is an indicator of poor clinical outcome.
