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Updated: Jul 2, 2025
Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
Published on: July 19, 2018
Prognosis of urgent initiation of peritoneal dialysis: a systematic review and meta-analysis
Ji He1,2, BaoQiao Wu3, Yue Zhang2
1Jinzhou Medical University, Jinzhou, Liaoning, China.
Insights
Initiating peritoneal dialysis (PD) within 7 days of catheter placement shows no difference in leakage or infection. However, early PD initiation (<7 days) may increase catheter displacement risk. Catheter survival and transition to hemodialysis remain unaffected.
Area of Science:
- Nephrology
- Renal Replacement Therapy
- Dialysis Techniques
Background:
- Optimal timing for initiating peritoneal dialysis (PD) post-catheter placement lacks consensus.
- Unplanned PD initiation, particularly within 14 or 7 days of catheter insertion, requires further safety and outcome assessment.
Conclusions:
- Unplanned PD initiation, even within 7 days, does not increase infectious complications compared to planned initiation.
- While early PD initiation (<7 days) may elevate catheter displacement risk, it does not compromise catheter survival or necessitate earlier conversion to hemodialysis.
Objectives:
Currently, there is no consensus on the optimal timing for the initiation of peritoneal dialysis (PD) after catheter placement.
Design:
Systematic review and meta-analysis.
Exact Date Of Data Collection:
From inception till July 31, 2023.
Main Outcome Measures:
To assess the outcomes and safety of unplanned PD initiation (<14/7 days after catheter insertion) in cohort studies.
Results:
Fifteen studies involving 3054 participants were included. (1) The risk of unplanned initiation of leakage and Obstruction was no difference in both the break-in period (BI) <14 and BI < 7 groups. (2) Catheter displacement was more likely to occur in the emergency initiation group with BI < 7. (3) No significant differences were observed between the two groups regarding infectious complications. (4) There was no difference in transition to HD between patients with BI < 7 and BI < 14 d.
Conclusion:
Infectious complications of unplanned initiation of peritoneal dialysis did not differ from planned initiation. Emergency initiation in the BI < 7 group had higher catheter displacement, but heterogeneity was higher. There were no differences in leakage or obstruction in either group. Catheter survival was the same for emergency initiation of peritoneal dialysis compared with planned initiation of peritoneal dialysis and did not increase the risk of conversion to hemodialysis.
Registration:
This meta-analysis was registered on PROSPERO (https://www.crd.york.ac.uk/PROSPERO/, number: CRD42023431369).
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