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Updated: Jul 19, 2026
07:42
An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
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A deep dive into the percutaneous mitral valve data
Ana Paula Tagliari1,2, Rodrigo Petersen Saadi1,3, Gilbert H L Tang4
1Universidade Federal do Rio Grande do Sul.
Current Opinion in Cardiology
|February 23, 2024
Summary
Percutaneous mitral valve interventions offer less invasive options for mitral regurgitation (MR) when surgery is not feasible. Transcatheter repair and replacement technologies are evolving, expanding treatment possibilities for high-risk patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Heart Valve Disease
Background:
- Mitral regurgitation (MR) is common, with surgery as the standard for primary MR.
- Many patients are ineligible for surgery due to high risk or specific criteria, especially with secondary MR.
- Transcatheter therapies provide less invasive alternatives for MR management.
Approach:
- Transcatheter leaflet repair techniques have advanced significantly, addressing diverse anatomical challenges.
- Evidence for transcatheter repair safety and efficacy comes from trials like EVEREST II, COAPT, MITRA-FR, and CLASP IID, plus registries.
- Transcatheter mitral valve replacement is an emerging option for patients unsuitable for leaflet repair, with ongoing clinical trials.
Key Points:
- Percutaneous mitral valve interventions are evolving rapidly.
- Transcatheter leaflet repair and replacement offer hope to patients unsuitable for traditional surgery.
- Pivotal trials and large registries guide the development and application of these minimally invasive techniques.
Conclusions:
- The field of percutaneous mitral valve interventions is continuously advancing.
- Innovative technologies like MitraClip and others are expanding treatment options.
- These advancements provide new hope for patients with mitral regurgitation who are not ideal surgical candidates.
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