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The urinary excretion of ionized and non-ionized calcium by rats treated with 1.25-dihydroxycholecalciferol
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme
|May 1, 1985
Abstract:
The administration of 1,25-dihydroxycholecalciferol to rats increased their calciuresis as a power function of the dose. Up to 95% of the urinary calcium was excreted as a non-ionized complex, together with equimolar amounts of citrate. The stoichiometry between calcium and citrate, observed at all dose levels, suggests that citrate metabolism is coordinated with the mobilization of calcium.