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A Rare Case of Complete-Immunotherapy-Responsive Metastatic Non-Small Cell Lung Cancer with Long Lasting

Claudia De Intinis¹, Paolo Izzo¹, Massimo Codacci-Pisanelli¹

¹Department of Surgery "Pietro Valdoni", Policlinico "Umberto I", "Sapienza" University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.

Current Oncology (Toronto, Ont.)

|February 23, 2024

Abstract

Background And Introduction:

Lung cancer is a prevalent and deadly disease globally. Non-small cell lung cancer (NSCLC) is the most common subtype, comprising 85% of cases.

Case Report:

A 65-year-old male ex-smoker presented to our facility with a nocturnal cough. Various investigations revealed that he had metastatic NSCLC, for which he underwent chemotherapy with cisplatin and gemcitabine, followed by immunotherapy with Nivolumab. He achieved a complete response to the therapy and has remained free from recurrence for over 7 years since the initial diagnosis.

Discussion And Conclusions:

The treatment of metastatic NSCLC remains a significant therapeutic challenge, but the implementation of new therapeutic techniques has expanded the possibilities of achieving complete and durable eradication of the disease.

Keywords:

NSCLC case report complete response immunotherapy literature review metastasis

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