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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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Related Experiment Video

Updated: May 3, 2026

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique
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Biopsy Techniques for Musculoskeletal Tumors: Basic Principles and Specialized Techniques.

Andreas F Mavrogenis1, Pavlos Altsitzioglou1, Shinji Tsukamoto2

  • 1First Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, 1 Rimini, 157 72 Athens, Greece.

Current Oncology (Toronto, Ont.)
|February 23, 2024
PubMed
Summary

Accurate bone and soft tissue tumor biopsies are crucial for diagnosis and survival. Liquid biopsies offer a promising, less invasive alternative for monitoring cancer progression and treatment response.

Keywords:
biopsyincisionalliquidpercutaneous

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Area of Science:

  • Oncology
  • Orthopedics
  • Pathology

Background:

  • Biopsy is essential for diagnosing bone and soft tissue tumors.
  • Ensuring diagnostic accuracy is vital to prevent tumor spread and ensure patient survival.

Purpose of the Study:

  • To review current principles and practices in musculoskeletal biopsies.
  • To explore liquid biopsies as an emerging alternative for tumor analysis.
  • To discuss challenges and risks associated with tumor biopsies.

Main Methods:

  • Comprehensive literature search across PubMed, Google Scholar, and library resources.
  • Review of research articles on biopsy techniques, principles, and specialized methods for tumor patients.
  • Analysis of advantages, disadvantages, mechanisms, risks, and complications of biopsy techniques.

Main Results:

  • Inadequate biopsies can negatively impact diagnosis and treatment outcomes.
  • Liquid biopsies show potential for non-invasive analysis of tumor characteristics and treatment guidance.
  • Barriers to liquid biopsy implementation include cost, scalability, and reproducibility.

Conclusions:

  • Accurate biopsy technique is paramount for effective musculoskeletal tumor management.
  • Collaboration between orthopedic oncologists, radiologists, and pathologists is key.
  • Liquid biopsies represent a significant advancement in non-invasive cancer diagnostics and monitoring.