Cardiovascular Complications in Patients with Heart Failure and COVID-19: CARDIO COVID 19-20 Registry

Area of Science:

• Cardiology
• Infectious Diseases
• Public Health

Background:

• Older adults with cardiovascular comorbidities face increased COVID-19 risk.
• Heart failure (HF) is a prevalent cardiovascular comorbidity.
• The impact of HF on COVID-19 prognosis requires further investigation.

Purpose of the Study:

• To assess the impact of pre-existing heart failure (HF) on COVID-19 patients.
• To evaluate HF's effect on cardiovascular complications, ICU admissions, and mortality.
• To analyze in-hospital and post-discharge outcomes in COVID-19 patients with and without HF.

Main Methods:

• Utilized the CARDIO COVID 19-20 registry (May 2020-June 2021).
• Included 3260 hospitalized COVID-19 patients from Latin America.
• Compared outcomes between patients with (n=182) and without previous HF.

Main Results:

• Patients with HF had higher incidence of supraventricular arrhythmia (16.5% vs 6.3%) and acute coronary syndrome (7.1% vs 2.7%).
• HF patients showed increased ICU admission rates (61.5% vs 53.1%) and in-hospital mortality (41.8% vs 24.5%).
• Cardiovascular mortality was significantly higher at discharge (42.1% vs 18.5%) and 30 days post-discharge (66.7% vs 18.0%) for HF patients.

Conclusions:

• A history of heart failure is associated with a more severe cardiovascular profile in COVID-19 patients.
• Pre-existing HF significantly increases the risk of cardiovascular complications and adverse outcomes.
• HF is a critical factor influencing COVID-19 severity and mortality, necessitating targeted management strategies.