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Published on: March 1, 2024
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Psoriasis and Fibromyalgia: A Systematic Review
Martina D'Onghia1, Francesco Ursini2,3, Elisa Cinotti1
1Department of Medical, Surgical and Neurological Sciences, Dermatology Section, University of Siena, 53100 Siena, Italy.
Journal of Personalized Medicine
|February 23, 2024
Summary
Psoriasis patients show a higher prevalence of fibromyalgia, a condition causing widespread pain. This review highlights a significant link between psoriasis and fibromyalgia, impacting symptom severity and outcomes.
Area of Science:
- Dermatology and Rheumatology
- Investigating the complex relationship between chronic inflammatory skin conditions and musculoskeletal syndromes.
Background:
- Psoriasis is a chronic inflammatory skin disease associated with various comorbidities.
- Psoriatic arthritis is a known comorbidity, but the link with fibromyalgia remains less explored.
Purpose of the Study:
- To systematically review existing literature on the association between psoriasis and fibromyalgia.
- To synthesize evidence regarding the prevalence and impact of fibromyalgia in psoriasis patients.
Main Methods:
- Systematic literature search conducted on MedLine and Web of Science (WOS) databases up to March 2023.
- Adherence to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
- Qualitative synthesis of 11 eligible studies.
Main Results:
- Psoriasis patients exhibited a significantly higher prevalence of fibromyalgia (8-30%).
- Fibromyalgia substantially impacts psoriasis symptom severity and outcomes, especially in patients with psoriatic arthritis.
- Fibromyalgia patients showed a slightly increased prevalence of psoriasis (2.2-6.7%) compared to controls.
Conclusions:
- Evidence suggests a potential interplay between psoriasis and fibromyalgia.
- Further research is warranted to fully elucidate the relationship and its clinical implications.
- Understanding this association may improve management strategies for patients with co-occurring psoriasis and fibromyalgia.
