Association between Dyslipidemia and Glycated Hemoglobin in a Population-Based Study
Purum Kang1, Ka Young Kim2, Hye Young Shin3
1College of Nursing, Woosuk University, Wanju 55338, Republic of Korea.
Metabolites
|February 23, 2024
Summary
High blood sugar, indicated by elevated glycated hemoglobin (HbA1c), significantly increases the risk of dyslipidemia in Korean adults. This association is particularly strong in individuals aged 40 and older, highlighting the need for monitoring lipid levels in this demographic.
Area of Science:
- Endocrinology
- Cardiovascular Health
- Public Health
Background:
- Diabetes mellitus and dyslipidemia are significant risk factors for cardiovascular disease.
- Prevalence of dyslipidemia and diabetes mellitus is increasing in Korean adults over 30.
- Glycated hemoglobin (HbA1c) is a key marker for glucose control.
Purpose of the Study:
- To investigate the association between dyslipidemia and high glycated hemoglobin (HbA1c) levels.
- To analyze this association across different age groups in Korean adults.
- To identify specific age demographics at higher risk.
Main Methods:
- Utilized data from the 7th Korea National Health and Nutrition Examination Survey (2016-2017).
- Categorized HbA1c into normal (<5.7%), prediabetes (5.7-6.4%), and diabetes (≥6.5%).
- Employed logistic regression analysis, adjusting for multiple confounders.
Main Results:
- Significant increase in odds ratios for dyslipidemia in prediabetes (OR 1.915) and diabetes (OR 3.533) groups.
- Individuals in their 40s and older with higher HbA1c showed significantly increased odds for dyslipidemia.
- A clear association was found between high HbA1c and diagnosed dyslipidemia in Korean adults.
Conclusions:
- High glycated hemoglobin (HbA1c) levels are significantly associated with dyslipidemia in Korean adults.
- Monitoring lipid metabolism is crucial for adults with elevated HbA1c, especially those aged 40 and above.
- This finding underscores the importance of managing blood glucose to prevent cardiovascular complications.
More Related Videos
07:29Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
9.3K
06:26Analyzing the Permeability of the Blood-Brain Barrier by Microbial Traversal through Microvascular Endothelial Cells
Published on: February 14, 2020
15.6K
Related Concept Videos
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
163
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
163
01:15Diabetes: Symptoms, Diagnosis, and Complications
539
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
539
01:22Diabetes Mellitus: Type 2 and Gestational
2.4K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.4K
01:24Overview of Lipid Metabolism
1.6K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
1.6K
01:11Genome-wide Association Studies-GWAS
13.4K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
13.4K
01:05Proteoglycans
3.9K
Glycans, a class of complex heterogeneous molecules, can be covalently attached to proteins to form glycosylated proteins that regulate various physiological and pathological processes. Glycosylated proteins or glycoproteins comprise N-linked and O-linked oligosaccharides. O-glycosylation is the most common type of protein glycosylation. Here, glycans attach to the oxygen atom of the hydroxyl groups of Serine or Threonine residues. O-linked glycosylation occurs later in protein processing,...
3.9K