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Related Experiment Video

Updated: Feb 14, 2026

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Coelomic fat ectopia in the liver.

D A Wheeler, H A Edmondson

    Archives of Pathology & Laboratory Medicine
    |August 1, 1985
    PubMed
    Summary

    This study details a rare liver mass composed of adipose tissue, smooth muscle, and blood vessels, potentially originating from ectopic coelomic mesenchyme. This finding suggests a novel origin for hepatic lipomas and other mesenchymal tumors.

    Area of Science:

    • Histopathology
    • Developmental Biology
    • Surgical Pathology

    Background:

    • Liver masses require precise classification for accurate diagnosis and treatment.
    • Understanding the origin of mesenchymal tumors is crucial for pathology.
    • Ectopic tissues can arise from developmental anomalies.

    Observation:

    • A pedunculated liver mass covered by mesothelium was identified within a mesothelial-lined sac.
    • Microscopic examination revealed mature adipose tissue, thick-walled arteries, large veins, fibrous tissue, and smooth muscle bundles.
    • An unclassifiable mesenchymal tumor was concurrently found in the cerebellum.

    Findings:

    • The liver lesion is hypothesized to be ectopic coelomic mesenchyme, possibly representing misplaced omentum or mesentery.

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  • This case suggests that hepatic lipomas may also originate from ectopic coelomic mesenchyme.
  • The relationship between the liver and cerebellar mesenchymal lesions remains undetermined.

    • Implications:

    • This discovery may necessitate re-evaluation of the pathogenesis of hepatic adipose tissue masses.
    • It highlights the potential for complex developmental anomalies involving mesenchymal tissues.
    • Further research is needed to explore the link between multiple mesenchymal lesions in different organs.