Research progress on microcirculatory disorders in septic shock: A narrative review
Hui Wang1, Hong Ding, Zi-Yan Wang
1Department of Intensive Care, Affiliated Hospital of Chengde Medical University, Chengde, China.
Medicine
|February 23, 2024
Summary
Maintaining hemodynamic coherence is crucial for septic shock survival. This review explores microcirculation monitoring and proposes integrating it with macrocirculatory parameters for better patient outcomes.
Area of Science:
- Critical care medicine
- Hemodynamics
- Microcirculation research
Background:
- Septic shock significantly impacts microcirculation, potentially leading to organ failure.
- Maintaining balance between macrocirculation and microcirculation is vital for patient outcomes.
- Current microcirculation monitoring methods are not widely adopted in clinical practice.
Approach:
- This review evaluates the effects of septic shock on microcirculation.
- It assesses current methods for monitoring microcirculation.
- The review proposes an integrated framework for macro- and microcirculatory monitoring.
Key Points:
- Microcirculatory disorders in septic shock have severe clinical consequences.
- Advanced monitoring tools are essential but face integration challenges.
- Hemodynamic coherence is critical for managing septic shock.
Conclusions:
- Integrating microcirculation monitoring with macrocirculatory parameters is proposed.
- Optimal monitoring should be dynamic, multiparametric, individualized, and continuous.
- This approach is particularly important in cases of hemodynamic separation during septic shock.
