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Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue
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Published on: February 24, 2023

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CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis

Simon Rauber1,2, Hashem Mohammadian1,2, Christian Schmidkonz3,4

  • 1Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.

Nature Immunology
|February 24, 2024
PubMed
Summary

Fibroblast activation protein (FAP) imaging reveals fibroblast phenotypic shifts during inflammation resolution. This transition from pro-inflammatory to pro-resolving states is crucial for healing arthritis.

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