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Myeloma cells in the urine
Archives of Pathology & Laboratory Medicine
|September 1, 1985
Summary
This case study reveals a rare instance of multiple myeloma affecting the urinary bladder. Myeloma cells were found in urine, originating from a bladder tumor, a previously undocumented source.
Area of Science:
- Hematology
- Urology
- Oncology
Background:
- Multiple myeloma is a plasma cell malignancy typically affecting bone marrow.
- Urinary tract involvement in multiple myeloma is uncommon.
- The presence of myeloma cells in urine usually indicates renal involvement or systemic spread.
Observation:
- A 71-year-old male patient with advanced multiple myeloma presented with unusual urinary findings.
- Myeloma cells were identified in the patient's urinary sediment.
- Autopsy revealed a plasmacytoma within the urinary bladder.
Findings:
- This case demonstrates a primary plasmacytoma of the urinary bladder as the source of myeloma cells in the urine.
- This represents a rare anatomical site for myeloma manifestation.
- The findings challenge the assumption that urinary myeloma cells solely indicate renal pathology.
Implications:
- Highlights the importance of considering unusual anatomical sites for myeloma infiltration.
- Suggests that urinary cytology may reveal bladder plasmacytomas in select multiple myeloma patients.
- Expands the understanding of the diverse clinical presentations of multiple myeloma.