Oxygen Saturation Increase in Ischemic Wound Tissues after Direct and Indirect Revascularization

Area of Science:

• Vascular Surgery
• Ischemic Wound Management
• Endovascular Interventions

Background:

• Restoring oxygen supply is key for ischemic wound treatment.
• Direct angiosomal revascularization's superiority over indirect methods is debated.
• Below-knee artery revascularization aims to improve tissue oxygenation.

Purpose of the Study:

• To compare intraoperative tissue oxygen saturation changes.
• To evaluate direct versus indirect revascularization in below-knee arteries.
• To assess the impact on ischemic zones.

Main Methods:

• Prospective observational study of endovascular revascularizations.
• Near-infrared spectroscopy monitored regional oxygen saturation (rSO2).
• Comparison of rSO2 changes between direct and indirect groups.

Main Results:

• Significant overall increase in regional oxygen saturation post-revascularization (p=0.001).
• No statistically significant difference in rSO2 increase between direct and indirect groups (p=0.619).
• Equal patient numbers in both direct (15) and indirect (15) revascularization groups.

Conclusions:

• Minor differences in oxygen saturation increase between angiosomal and non-angiosomal revascularization.
• Clinical significance of angiosomal revascularization may be negligible.
• Confounding factors like vessel diameter and outflow may influence restenosis rates.