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Myocardial Injury after Non-Cardiac Surgery in Patients Who Underwent Open Repair for Abdominal Aortic Aneurysm: A

Myung Il Bae1, Tae-Hoon Kim2, Hei Jin Yoon1

  • 1Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.

Journal of Clinical Medicine
|February 24, 2024
PubMed
Abstract

Insights

Myocardial injury after non-cardiac surgery (MINS) is common after abdominal aortic aneurysm (AAA) repair and significantly increases 30-day and 1-year mortality risk. Patients with MINS face poorer overall survival rates.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Critical Care Medicine

Background:

  • Myocardial injury after non-cardiac surgery (MINS) is linked to mortality in surgical patients.
  • The prognostic significance of MINS following abdominal aortic aneurysm (AAA) open repair is not well-established.
  • This study addresses the underexplored role of MINS in AAA open repair outcomes.

Purpose of the Study:

  • To investigate Myocardial Injury after Non-cardiac Surgery (MINS) as a predictor of mortality.
  • To assess the prognostic value of MINS in patients undergoing open repair for abdominal aortic aneurysm (AAA).

Main Methods:

  • Retrospective analysis of 352 patients undergoing open repair for non-ruptured AAA.
  • Logistic regression analysis was employed to identify predictors of 30-day and 1-year mortality.
  • Kaplan-Meier survival analysis was used to compare survival rates between groups.

Main Results:

  • Myocardial Injury after Non-cardiac Surgery (MINS) occurred in 41% of patients post-AAA open repair.
  • MINS was an independent risk factor for 30-day mortality (OR: 10.440) and 1-year mortality (OR: 5.189).
  • Patients with MINS exhibited significantly lower overall survival rates (p = 0.003).

Conclusions:

  • Myocardial Injury after Non-cardiac Surgery (MINS) is a frequent complication after AAA open repair.
  • MINS independently predicts increased 30-day and 1-year mortality.
  • MINS is associated with reduced overall survival in patients undergoing AAA open repair.
Keywords:
abdominal aortic aneurysmabdominal aortic aneurysm open repairmortalitymyocardial injury after non-cardiac surgery

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