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Effect of Polyphenol Supplementation on Memory Functioning in Overweight and Obese Adults: A Systematic Review and Meta-Analysis

  • 0Department of Psychology, Edge Hill University, Ormskirk L39 4QP, UK.
Nutrients +

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February 24, 2024

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February 24, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Polyphenol supplements may improve immediate memory recall in older adults with obesity. However, evidence for benefits on delayed recall remains inconclusive, suggesting further research is needed.

Area Of Science

  • Neuroscience
  • Nutritional Science
  • Gerontology

Background

  • Obesity is linked to cognitive decline and neuronal damage.
  • Polyphenols possess antioxidant properties, but their impact on cognition is debated.
  • Existing research lacks clarity on polyphenol effects on specific cognitive processes.

Approach

  • A systematic review and meta-analysis of 24 randomized controlled trials.
  • Included participants (N=2336) had a Body Mass Index (BMI) ≥ 25.0 kg/m² and were over 60 years old.
  • Focused on polyphenol effects on immediate and delayed information retrieval tasks.

Key Points

  • Meta-analysis revealed a significant positive effect of polyphenols on immediate retrieval.
  • No significant effect was observed for delayed retrieval.
  • Flavonoids were the most noted polyphenols in positive outcomes.

Conclusions

  • Chronic polyphenol supplementation may benefit immediate memory in older adults with obesity.
  • Obesity is a risk factor for cognitive impairment, highlighting the need for targeted interventions.
  • Future studies should specify phenolic content and cognitive processes tested.

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