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Fixed-Dose Combination Formulations in Solid Oral Drug Therapy: Advantages, Limitations, and Design Features

Christi A Wilkins1, Hannlie Hamman1, Josias H Hamman1

  • 1Centre of Excellence for Pharmaceutical Sciences (Pharmacen™), Faculty of Health Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa.

Pharmaceutics
|February 24, 2024
PubMed
Summary

Fixed-dose combination (FDC) therapy offers an alternative to sequential drug addition for complex conditions. This review critically examines FDC drug therapy, its benefits, and challenges in patient adherence.

Keywords:
fixed-dose combination therapyformulation approaches/technologyformulation considerations

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