Non-Hodgkin's lymphoma in pregnancy

Pregnancy in patients who have non-Hodgkin's lymphoma is unusual. We have reported a case of diffuse, poorly differentiated lymphocytic lymphoma, stage IIIa, in a patient whose disease went into remission after she received six courses of CHOP therapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone). She became pregnant soon afterward and was delivered of a normal, full-term infant with a normal chromosomal pattern. Risk of teratogenicity appears to be negligible when chemotherapy is used during the third trimester of pregnancy.