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Updated: Jul 2, 2025

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
Published on: August 5, 2021
[Progress in antibacterial coatings of titanium implants surfaces]
Xuhong He1, Chaiqiong Guo1, Xuanyu Liu1
1Department of Biomedical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Research Center for Nanobiomaterials and Regenerative Medicine, Taiyuan 030024, P. R. China.
Abstract:
In recent years, bone implant materials such as titanium and titanium alloys have been widely used in the biomedical field due to their excellent mechanical properties and good biocompatibility. However, in clinical practice, bacterial adhesion to the material surface and postoperative infection issues may lead to implantation failure. Based on the antibacterial mechanism, this review elaborated on the antibacterial surface design of titanium implants from the aspects of anti-bacterial adhesion, contact sterilization and photocontrol sterilization. Surface modification of titanium or titanium-based alloy implants with different techniques can inhibit bacteria and promote osseointegration. Thus, the application range of multifunctional titanium-based implants in the field of orthopedics will be expanded.

