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Updated: Jul 24, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
The catastrophic association of prosthetic mitral valve thrombosis and hemorrhagic stroke
Humberto Morais1,2, Mauer A A Gonçalves1,3
1Centro de Estudos Avançados em Educação e Formação Médica, Faculdade de Medicina da Universidade Agostinho Neto, Luanda, Angola.
Abstract:
Prosthetic valve thrombosis is a serious complication of valve replacement associated with a high mortality rate. Stroke may be the first symptom of prosthetic valve thrombosis. We present the case of a patient who visited the emergency department with symptoms of dysarthria and left hemiparesis. An examination revealed an ischemic stroke with hemorrhagic transformation, stemming from a thrombosis of their mitral valve prosthesis, which progressed to the patient's death. We emphasize the difficulty in the therapeutic and diagnostic management of these patients.
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