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Updated: May 5, 2026

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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
14.4K
Structural aortic wall abnormalities following the Nikaidoh operation, which could be reversible and include a
Magdi H Yacoub1, Ahmed Afifi2, Hatem Hosny2
1Magdi Yacoub Institute, National Heart and lung Institute, Imperial College London, London, UK.
Global Cardiology Science & Practice
|February 26, 2024
Summary
The Nikaidoh operation for complex heart defects can lead to aortic root issues. This study details extensive structural changes in the aortic wall following this procedure, requiring re-operation.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Aortic Pathology
Background:
- The Nikaidoh operation is a recognized surgical approach for complex congenital heart defects.
- Recent follow-up revealed significant aortic root alterations after the Nikaidoh procedure, necessitating re-operation.
- The underlying pathophysiology and reversibility of these aortic root changes remain uninvestigated.
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