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Longitudinal Case-Control Study of Active and Passive Dense Mammographic Breast Tissue
Medrxiv : the Preprint Server for Health Sciences
|February 26, 2024
Summary
New mammography analysis using the Hurst exponent (H) identifies distinct tissue types. Active dense tissue indicates cancer risk, while passive dense tissue may signal developing breast cancer years before detection.
Area of Science:
- Radiology and Medical Imaging
- Biophysics
- Oncology
Background:
- Mammography is crucial for breast cancer secondary prevention.
- Current methods struggle to link mammographic findings to early cancer development.
- Primary prevention requires understanding sub-mammographic changes preceding detectable cancer.
Conclusions:
- Active dense tissue identified via the Hurst exponent is a risk factor for breast cancer.
- Passive dense tissue may serve as an early indicator of developing breast cancer.
- Hurst exponent analysis offers a novel approach for early breast cancer risk assessment and primary prevention.

