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Updated: May 27, 2026

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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DexDesign: A new OSPREY-based algorithm for designing de novo D-peptide inhibitors.

Nathan Guerin, Henry Childs, Pei Zhou

    Biorxiv : the Preprint Server for Biology
    |February 26, 2024
    PubMed
    Summary

    Researchers developed DexDesign, a computational tool for creating novel D-peptide inhibitors targeting PDZ domains. These D-peptides show potential as therapeutics for diseases like cancer and cystic fibrosis.

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