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Related Experiment Videos

[Embolisms in the embryo].

M Schneider, J Rickenbacher

    Acta Anatomica
    |January 1, 1985
    PubMed
    Summary

    Artificial embolisms in chick embryos showed that most obstructed vessels recanalized within 10 hours. Thrombocytes surrounded the emboli, aiding their transport and interaction with vessel walls.

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    Area of Science:

    • Developmental biology
    • Vascular biology
    • Embryology

    Context:

    • Investigating the early vascular response to artificial emboli in a developing organism.
    • Utilizing chick embryos as a model for studying microvascular obstruction and recanalization.

    Purpose:

    • To examine the fate of artificial emboli introduced into the chick embryo's extraembryonic vasculature.
    • To elucidate the role of thrombocytes in the transport and interaction of emboli within developing blood vessels.

    Summary:

    • Artificial embolisms were created in chick embryos using mouse liver cell particles injected into an extraembryonic vein.
    • Microscopic examination of serial sections revealed that most obstructed vessels underwent recanalization within 1-10 hours post-injection.
    • Emboli were consistently surrounded by thrombocytes, adhered to vessel walls, and smaller particles were observed in the surrounding mesenchyme.

    Impact:

    • Provides insights into the dynamic processes of vascular recanalization in embryonic development.
    • Highlights the potential role of thrombocytes in managing vascular obstructions and particle transport.
    • Offers a model for studying embolism resolution and tissue response in a developing system.

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