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Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
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Smart Contact Lenses for Healthcare Monitoring and Therapy.
Xiaohu Liu1, Ying Ye1, Yuancai Ge1
1School of Ophthalmology and Optometry, Eye Hospital, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325001, China.
ACS Nano
|February 26, 2024
Summary
Smart contact lenses offer noninvasive disease monitoring using ocular biomarkers. This review covers their development for diagnostics, drug delivery, and future bioapplications.
Area of Science:
- Ophthalmology and Biomedical Engineering
- Wearable Sensor Technology
Background:
- The eye provides a unique, noninvasive site for physiological monitoring.
- Smart contact lenses are emerging as intelligent wearable sensing platforms.
- Current applications are in early stages for disease monitoring and therapy.
Purpose of the Study:
- To review smart contact lenses for disease monitoring and therapy.
- To summarize ocular biomarkers, materials, and manufacturing processes.
- To discuss advancements in drug delivery, diagnostics, and bioapplications.
Main Methods:
- Comprehensive literature review of smart contact lens research.
- Analysis of ocular biomarkers (physical and chemical).
- Evaluation of materials, manufacturing, and sensor technologies.
Main Results:
- Identification of various ocular biomarkers for disease detection.
- Overview of smart contact lens technologies for drug delivery and diagnostics.
- Discussion of sensor communication, antimicrobial applications, and future prospects.
Conclusions:
- Smart contact lenses hold significant potential for noninvasive disease management.
- Further development is needed to overcome challenges in sensor integration and application.
- Emerging bioapplications and advanced technologies promise enhanced therapeutic and diagnostic capabilities.

