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Development of STING degrader with double covalent ligands

Miki Nakamura1, Nobumichi Ohoka2, Norihito Shibata3

  • 1Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Division of Pharmaceutical Science of Okayama University, 1-1-1, Tsushimanaka, Kita 700-8530, Japan; Division of Organic Chemistry, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki, Kanagawa 210-9501, Japan.

Bioorganic & Medicinal Chemistry Letters
|February 26, 2024
PubMed

Keywords:
Covalent ligandDrug designProtein degradationSTING

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