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[Legionnaires' disease (author's transl)].

A Arderiu Freixa, P Coll Figa, J L Bada Ainsa

    Medicina Clinica
    |August 15, 1979
    PubMed
    Summary
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    Legionnaires' disease is a severe infectious pneumonia caused by Gram-negative bacteria. Diagnosis involves special stains or culture, with erythromycin as the primary treatment.

    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Public Health

    Context:

    • Legionnaires' disease, a severe pneumonia, has been diagnosed globally, including Spain.
    • The disease primarily affects individuals in their fifth decade of life.
    • It often presents with gastrointestinal symptoms and hyponatremia, particularly during summer outbreaks.

    Purpose:

    • To review and update current knowledge on Legionnaires' disease.
    • To highlight diagnostic methods and treatment options.
    • To emphasize the clinical presentation and epidemiological patterns.

    Summary:

    • Legionnaires' disease is caused by a fastidious Gram-negative bacterium requiring specialized stains or enriched media for identification.
    • Clinical manifestations include atypical pneumonia, gastrointestinal distress, and characteristic hyponatremia.

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  • Diagnosis is confirmed via direct identification (staining, culture) or serological testing.
  • Erythromycin is the recommended antibiotic, potentially combined with a broader-spectrum agent.

    • Impact:

    • Provides a comprehensive overview for clinicians and researchers.
    • Emphasizes the importance of early diagnosis and appropriate treatment.
    • Contributes to understanding the epidemiology and severity of Legionnaires' disease, with a 15-20% mortality rate.