Routine results of an algorithm for managing the production of blood components
Ana Isabel Pérez-Aliaga1, Irene Ayerra2, Javier Sánchez-Guillén1
1Blood and Tissues Bank of Aragón (BTBA), Zaragoza, Aragón, Spain.
Vox Sanguinis
|February 27, 2024
Summary
An algorithm optimized blood component processing, significantly reducing platelet concentrate outdating by 87.8% and increasing plasma yield. This blood banking solution enhances efficiency and reduces waste.
Area of Science:
- Blood banking and transfusion medicine
- Bioprocess engineering
- Health informatics
Background:
- Increasing demand for blood components and plasma-derived medicines necessitates optimized blood processing.
- Variability in blood donations presents challenges for blood banks.
- Existing mathematical models aim to improve blood banking efficiencies.
Purpose of the Study:
- To validate and assess the impact of a novel algorithm on blood component production.
- To evaluate the algorithm's effectiveness in a real-world blood bank setting.
Main Methods:
- A mathematical algorithm was developed, simulated with real data, and implemented in the fractionation area.
- The Reveos® fractionation system was utilized for blood component separation.
- Retrospective data from before and during algorithm use were compared over 9 months.
Main Results:
- Platelet concentrate (PC) outdating decreased by 87.8% within the blood bank.
- The shelf life of PCs supplied to transfusion services increased by nearly one day.
- An additional 100 liters of plasma were recovered over 9 months, and network outdating decreased by 33%.
Conclusions:
- The algorithm streamlines blood establishment workflows and decision-making for whole blood processing.
- Implementation led to reduced PC outdating, extended PC shelf life, and increased plasma recovery.
- These improvements result in significant cost savings for blood banking operations.
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