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The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
Published on: March 8, 2019
Pulmonary Artery Hypertension: Fifty Years Following Pneumonectomy in Infancy
Matthew Seplowe1, Ameesh Isath2, Liana Michaud1
1From the Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY.
Abstract:
Pulmonary hypertension (PH) may be the result of many different pathological processes. PH is a rare but recognized vascular complication following major lung resection. We describe the diagnosis and management of moderate PH resulting more than 50 years in a patient who underwent a total unilateral pneumonectomy in infancy. Unfortunately, patients who undergo pneumonectomy will likely go on to develop PH and their functional status will be greatly impacted. In the case presented, we report on a patient whose PH and symptoms improved following off-label WHO group 1 treatment.
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