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Published on: January 27, 2019
Bolus Feeding Via Gastric Versus Oral Routes in Very Preterm Neonates.
Rita P Verma1, Deepank Sahni2, Joshua Fogel3
1Nassau University Medical Center, East Meadow, NY 11554, NYC Health+ Hospitals/South Brooklyn Hospital, Coney Island, NY 11235.
Nipple bottle feeding, not bolus orogastric tube feeding, accelerates growth and reduces hospitalization in very premature neonates. Early nipple feeding initiation may be safe for stable infants, while antibiotics prolong hospital stays.
Area of Science:
- Neonatology
- Pediatric Nutrition
- Growth and Development
Background:
- Investigating feeding methods in very premature neonates (VPN) born between 28-33 weeks gestational age.
- Comparing bolus orogastric tube (BOG) and nipple bottle (N) feeding impacts on postnatal growth.
Purpose of the Study:
- To determine the association of BOG and N feedings with postnatal growth outcomes in VPN.
- To evaluate the effect of feeding methods on time to full enteral nutrition, weight gain, and length of hospitalization.
Main Methods:
- Retrospective analysis of clinical and feeding variables in 127 VPN.
- Multivariate regression and correlation analyses to assess associations between feeding methods and outcomes.
- Key outcomes included time to full enteral nutrition (FEN), weight to 2200g (Wt22), and length of hospitalization (LOH).
Main Results:
- FEN was negatively associated with gestational age and LOH, and Wt22 with birth weight.
- FEN positively correlated with days requiring intravenous nutrition and time to nipple feeding.
- LOH associated with antibiotic duration and time to nipple feeding; Wt22 associated with time to nipple feeding.
- BOG feeding start day showed no independent associations but weak positive correlations with Wt22, LOH, and FEN.
Conclusions:
- Bolus orogastric tube feeding alone does not independently affect growth, hospitalization, or time to full enteral nutrition in VPN.
- Nipple bottle feeding accelerates catch-up growth, full enteral nutrition, and reduces hospitalization duration.
- Initiating nipple feeding around 32 weeks postmenstrual age appears safe for stable VPN; antibiotics increase hospitalization.
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