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Updated: May 6, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Can 3-dimensional cranial ultrasound be used to successfully reconstruct a 2-dimensional image without compromising
Rachel M Roberts1, João Alves Rosa2, Siân Curtis3
1Department of Neuroradiology, West Wing Level 1, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK. Rachel.roberts@ouh.nhs.uk.
Background:
Cranial ultrasound is frequently performed in neonatal intensive care units and acquiring 2-dimensional (D) images requires significant training. Three-D ultrasound images can be acquired semi-automatically.
Objective:
This proof-of-concept study aimed to demonstrate that 3-D study image quality compares well with 2-D. If this is successful, 3-D images could be acquired in remote areas and read remotely by experts.
Materials And Methods:
This was a prospective study of 20 neonates, who underwent both routine 2-D and 3-D cranial ultrasounds. Images were reconstructed into standard views extracted from the 3-D volume and evaluated by three radiologists blinded to the acquisition method. The radiologists assessed for the presence of anatomical landmarks and overall image quality.
Results:
More anatomical structures were identified in the 3-D studies (P<0.01). There was a trend that 3-D ultrasound demonstrated better image quality in the coronal plane, and 2-D in the sagittal plane, only reaching statistical significance for two coronal views and two sagittal views.
Conclusion:
Overall, this study has demonstrated that 3-D cranial ultrasound performs similarly to 2-D and could be implemented into neonatal practice.
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