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IgG4 disease with multiorgan involvement: a case report
M N Vidanapathirana1, D Wijayaratne2
1Professorial Medical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka. manudi.vidanapathirana@gmail.com.
Journal of Medical Case Reports
|February 28, 2024
Summary
This case study details a rare IgG4-related disease (IgG4RD) presentation affecting lungs, kidneys, and nerves. Early diagnosis using clinical, imaging, and pathology criteria led to effective steroid treatment and symptom improvement.
Area of Science:
- Rheumatology
- Immunology
- Rare Diseases
Background:
- Immunoglobulin G4-related disease (IgG4RD) is a rare, chronic fibroinflammatory condition affecting multiple organs.
- IgG4RD often presents insidiously over years, posing diagnostic challenges due to atypical symptoms and delayed consideration.
- Failure to include IgG4RD in differential diagnoses contributes to diagnostic delays.

