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Metastatic sclerosing epithelioid fibrosarcoma
Ryan C Rizk1, Mohammad Yasrab1, Linda C Chu1
1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 North Caroline St, Baltimore, MD 21287 USA.
Radiology Case Reports
|February 28, 2024
Summary
Sclerosing epithelioid fibrosarcoma, a rare cancer, often recurs or spreads. This case highlights the crucial role of radiological imaging in its accurate diagnosis and management.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Sclerosing epithelioid fibrosarcoma (SEF) is a rare variant of fibrosarcoma.
- SEF has a high rate of local recurrence and metastatic spread, affecting over half of patients.
- Limited and nonspecific imaging data exists for SEF, leading to diagnostic challenges.
Observation:
- A 27-year-old female presented with a growing mass in her right gluteus maximus muscle.
- The mass was diagnosed as metastatic sclerosing epithelioid fibrosarcoma.
- Radiological imaging modalities were utilized for diagnosis.
Findings:
- The study correlates radiological imaging findings with pathological results in a case of metastatic SEF.
- Imaging plays a key role in optimizing the diagnosis of this rare malignancy.
- Accurate and prompt diagnosis is critical due to the poor prognosis and high metastatic potential.
Implications:
- Improved diagnostic accuracy through advanced imaging can lead to earlier treatment interventions.
- Enhanced understanding of SEF imaging characteristics may reduce misdiagnosis rates.
- This case underscores the importance of multimodal diagnostic approaches for rare sarcomas.

